Centrifugation-Free sperm separation device surpasses conventional density – gradient centrifugation in ICSI cycles: higher blastulation, euploidy and lower mosaic rates
Conventional sperm separation using centrifugation in ART faces criticism for potential sperm harm, leading to the development of alternatives like LensHooke® CA0 (Bonraybio, Taiwan) (Figure 1). CA0, a centrifugation-free device, selects self-propelling spermatozoa within a microenvironment created by a microporous filter membrane. Studies indicate CA0 improves sperm DNA fragmentation, motility, and normal morphology (Wang et al., 2023). This study compares laboratory outcomes between CA0 and conventional density-gradient centrifugation (DGC) in ICSI cycles.
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