Our Numerous 1st Milestones

Our Doctors, Embryologists and staff through ALPHA IVF & the other fertility centres we worked with, produced numerous 1sts:

  • The WORLD’s 1st successful pregnancy using definitive high-resolution HLA (Human Leukocyte Antigen) genotyping from a single PGT biopsy in Saviour Sibling Programme from a monogenic disorder. (62nd All India Congress of Obstetrics & Gynaecology (AICOG), Bengaluru, India, 8-12 Jan 2019)
  • The WORLD’s 1st to demonstrate that combining a Day 5 and Day 6 Blastocyst results in very high pregnancy rates (Clinical Pregnancy Rate: 71.4%, Implantation Rate: 46.4%). (6th Congress of the Asia Pacific Initiative on Reproduction, Jakarta, Indonesia, 8 – 10th April 2016)
  • The WORLD’s 1st successful live birth following frozen embryo transfer of a 1PN embryo after PGD-MaCGH analysis. (14th International Conference on PGD, Chicago, USA 2015)
  • The WORLD’s 1st to demonstrate that embryos derived from conventional IVF have lower aneuploidy rates compared to embryos derived from ICSI. (13th International Conference on PGD. Cantebury, UK, May 2014)
  • The WORLD’s 1st to demonstrate similar euploidy rates among D3 apronuclear (0PN), unipronuclear (1PN) and 2 PN embryos using MaCGH analysis. (12th International Conference on PGD. Istanbul, Turkey, May 2013)
  • The WORLD’s 1st reported successful pregnancy following the use of freeze-thawed sperm, freeze-thawed eggs, and freeze-thawed embryoes. (10th Royal College of O&G International Scientific Congress, June 2012)
  • The WORLD’s 1st successful pregnancy and delivery in a patient with Mullerian Dysgenesis (a woman born without a vagina). (Reproductive BioMedicine Online, Vol 24, Issue 5, Pages 547-549), (May 2012)
  • The WORLD’s 1st successful pregnancy and delivery following PGD-CGH diagnosis of chromosome inversion. (11th International Conference on PGD, May 17th – 19th 2012, Austria)
  • The WORLD’s 1st PRP treatment for Ashermann’s Syndrome with resulting successful pregnancy and delivery (2010)
  • The WORLD’s 1st to show that an older uterus (about 40 years old) achieves similar pregnancy rates compared to uterus less than 30 years old. (Reproductive Biomedicine Online, 16(SUPPI2):S37-38 2008)
  • The WORLD’s 1st to demonstrate the importance of embryo transfer duration on pregnancy outcome. (14th World Congress on IVF and 3rd World Congress on IVM. Montreal, Canada. 15-19 September 2007)
  • The WORLD’s 1st reported delivery following the salvage of a presumably abnormal embryo. (7th Congress of PGDIS. Melbourne, Australia 13-15 June 2007)
  • Asia & Australia’s 1st successful pregnancy following world’s only proven sperm sorting technology after PGD-MaCGH analysis. (2015)
  • Asia & Australia’s 1st successful pregnancy following world’s only proven sperm sorting technology after Intracytoplasmic Sperm Injection (ICSI). (2015)
  • Asia & Australia’s 1st successful pregnancy following PGD-CGH diagnosis of chromosome translocation. (10th Royal College of O&G International Scientific Congress June 2012)
  • Asia & Australia’s 1st pregnancies and babies through Micro-Array Comparative Genomic Hybridisation PGD for 24 chromosomes with fresh transfer. (2011)
  • South East Asia’s 1st to achieve 100% survival for frozen blastocysts (2013)
  • South East Asia’s 1st to achieve 100% survival for frozen embryos (2013)
  • South East Asia’s 1st IVF Surrogate Baby (1995)
  • South East Asia’s 1st to achieve successful pregnancy using artificial intelligence (AI)-enhanced embryo selection technology (March,2021)
  • Malaysia & Singapore’s 1st PGD-PCR pregnancy for Alpha Thalassemia (2009)
  • Malaysia & Singapore’s 1st In-Vitro Maturation (IVM) pregnancy (2008)
  • Malaysia & Singapore’s 1st PGD for chromosomal translocation (2008)
  • Malaysia & Singapore’s 1st vitrified-warmed blastocyst PGD pregnancy (2008)
  • Malaysia & Singapore’s 1st Frozen embryo PGD baby (2006)
  • Malaysia & Singapore’s 1st sequential transfer PGD pregnancies (Day 3 and Day 6) (2006)
  • Malaysia & Singapore’s 1st PGD twins (2005)
  • Malaysia & Singapore’s 1st blastocyst biopsied PGD baby (2005)
  • Malaysia & Singapore’s 1st pregnancy following PGD (2004)
  • Malaysia’s 1st successful pregnancy for Alpha Thalassemia using PGD with concurrent PGS on a single platform from a single biopsy (2015)
  • Malaysia’s 1st Rescue-ICSI twin babies (2009)
  • Malaysia’s 1st conception quadruplets (2 babies born each time 1.5 years apart) (2003)
  • Malaysia’s 1st freeze-thaw blastocyst transfer pregnancy (2003)
  • Malaysia’s 1st blastocyst transfer IVF baby (2002)
  • Malaysia’s 1st sperm donor blastocyst transfer IVF baby (2002)
  • Malaysia’s 1st blastocyst transfer ICSI baby (2002)
  • Malaysia’s 1st Mesa-ICSI blastocyst transfer baby (2002)
  • Malaysia’s 1st donated frozen embryo pregnancy (1999)
  • Malaysia’s 1st conception twins born 1.5 years apart (1997)
  • Malaysia’s 1st frozen embryo baby (1996)
  • Malaysia’s 1st successful TEST (Tubal Embryo Transfer)(1989)
  • Malaysia’s 1st successful PROST (Pronuclear Transfer) baby (1988)
  • Malaysia’s 1st successful GIFT twins (1987)
  • Malaysia’s 1st IVF Baby delivered (1986)
  • Demonstrated successful twin pregnancy following transfer of a 2PN and 0PN embryo after PGD-MaCGH analysis. (ASRM, Baltimore, USA, 2015)
  • Demonstrated that 1PN embryos can be normal & therefore should not be discarded. (14th International Conference on PGDIS, Chicago, USA, 2015)
  • Demonstrated the safety of fertilization without ICSI for embryos undergoing PGS. (13th PGDIS 2014, Canterbury, UK)
  • Achieved Malaysia’s highest IVF clinical pregnancy and take-home baby rates
  • Produced the highest number of test-tube babies born in Malaysia
  • Pioneered the successful application of Comparative Genomic Hybridisation for testing embryos with chromosomal inversion and translocation. (11th International Conference on PGD, 2012, Austria & 10th Royal College of O&G International Scientific Congress, 2012)
  • Achieved Malaysia’s highest GIFT clinical pregnancy and take-home baby rates
  • Developed a mathematical formula to guide doctors on appropriate quantum of ovarian drilling. (Life, Issue 9, Page 14-16, 2007)
  • Demonstrated the value of tube rinsing in oocyte recovery procedure. (14th World Congress on IVF & 3rd World Congress on IVM. Montreal, Canada, 2007)
  • Demonstrate the importance of embryo transfer duration on pregnancy outcome. (14th World Congress on IVF and 3rd World Congress on IVM. Montreal, Canada, 2007)
  • Demonstrated that 0PN embryos can be normal & therefore should not be discarded. (7th Congress of PGDIS. Melbourne, Australia, 2007)
  • Developed a highly-effective technique protocol and communication system for embryo transfer. (ASRM, 2005)
  • Produced 11 consecutive ART pregnancies – obtained higher IVF pregnancy rates compared to all 67 IVF centres in the UK (2001)
  • Invented a womb mimicking machine called “SHOOGLE” (Patent pending)

ALL THE ABOVE ARE ACHIEVED BY DOCTORS, EMBRYOLOGISTS, AND STAFF THAT NOW CONSTITUTE ALPHA IVF & WOMEN’S SPECIALISTS

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