Our Success Rates

UNDERSTANDING IVF SUCCESS RATES

Since its introduction in the year of 1970s, IVF success rates have increased by leaps and bounds in the IVF industry. From a mere low 10 over percent, it has now reached up to 80 over percent, through innovative treatment procedures and advanced technologies.

As a couple considering an IVF treatment, it is important to understand what success rates really mean in order to distinguish between clinical and individual success rates.

In general, success rate depends on variable factors such as :

Maternal Age
Cause of Infertility
Embryo Status
Reproductive History
Lifestyle Factors

OUR IVF SUCCESS RATES

Below are our IVF clinical pregnancy rates per embryo transfer based on all IVF treatments throughout 2018.

A clinical pregnancy is a pregnancy that is confirmed by both high levels of hCG (the pregnancy hormone) and ultrasound confirmation of a gestational sac or heartbeat , which is usually detected using a handheld Doppler .

As you can see from the table above, our frozen embryo transfer success rates are higher compared to fresh embryo transfer success rates.

With the deployment of the revolutionary Cryotec® freezing technology that ALPHA IVF has been using since 2013, it is evident that IVF treatments performed along with frozen embryo transfer is a more of an effective means of treatment, and thus an ideal choice to make. Pregnancy success rates are relatively higher for patients who have undergone Preimplantation Genetic Testing for Aneuploidies (PGT-A) to enable the selection of chromosomally normal embryo for transfer, than those without PGT-A.

Do note that individual results may vary with individual circumstances, and not every treatment cycle will result in an egg collection, an embryo transfer or embryo cryopreservation.

OUR PUBLISHED IVF SUCCESS RATES

Revolutionary technologies that have been introduced in IVF play an important role in affecting IVF success rates. In being a patient of ALPHA IVF, you have access to the region’s leading innovative fertility treatment procedures and technologies that gives you IVF success rates that are comparable to top IVF centres worldwide.

The following outlines our published IVF success rates in 4 categories –

  • Blastocyst Transfer Program
  • IVF with and without PGS
  • Frozen Embryo Transfer Program (FET)
  • Donor Program.

Blastocyst Transfer Program

Fresh blastocyst transfer at ALPHA IVF yields high clinical pregnancy and implantation rates and avoids higher order multiple pregnancies. The table below shows a review of ALPHA IVF’s Blastocyst Transfer Program*.

blastocyst transfer program chart

*Lee CSS, Lim YX, Low SY (Alpha Fertility Centre). Fresh blastocyst transfer yields high clinical pregnancy and implantation rates and avoids higher order multiple pregnancies. Presented at the 23rd Malaysian Congress of the Obstetrical & Gynaecological Society of Malaysia, 5-8 June 2014, Selangor, Malaysia (Selected as one of the top 8 best abstracts).

Fresh blastocyst transfer from day 5 – 6, Non PGS, ICSI Mean number of blastocysts transferred is 2.0

IVF with and without Preimplantation Genetic Screening (PGS)

IVF failure is often due to unknowingly transferring embryos which are chromosomally abnormal. By applying PGT-A or previously known as PGS, only embryos with the correct number of chromosomes (euploid) are transferred, hence improving pregnancy rates.

The graphs below show the clinical pregnancy rates for patients with and without PGS*.

Clinical Pregnancy Rate (Stratified by Age Group)
July 2013 – December 2015

 

*Low SY, Lee CSS, Lim YX (Alpha Fertility Centre). Euploid blastocysts show a trend of higher implantation and clinical pregnancy rates compared to untested blastocysts in FET cycles. Reproductive Biomedicine Online 2016;32(S1):S21 (Presented at 11th Alpha Biennial Congress, 5 – 8th May 2016, Copenhagen, Denmark)

World Class Success Rate 79.5%*

We also demonstrated that transfer of a single good graded euploid blastocyst produces pregnancy rates as high as 79.5%.


Good graded euploid blastocyst transfer

*Lee CSS, Low SY, Lim YX, Keith J (Alpha Fertility Centre). Vitrified-warmed good graded euploid blastocysts aged <120 hours at the time of transfer yield superior clinical pregnancy and implantation rates . (Presented at 24th Congress of the Obstetrical and Gynaecological Society of Malaysia, 2-5th June 2016, Kuala Lumpur, Malaysia.)

* Clinical pregnancy rate from the transfer of vitrified-warmed good graded euploid blastocysts aged <120hours at the time of transfer, ICSI.
Mean age 32.1 (range 18-41 including autologous and egg donor)
Study period : July 2013 – December 2015

Donor Egg Program

Egg donation makes pregnancy possible for women who might not otherwise be able to get pregnant using their own eggs. ALPHA IVF has one of the best egg donation programs in Malaysia. Regardless of fertility history, all recipients of all ages have almost an equal chance of success.

*Leong, WY; Lee, CSS; Low SY (Alpha Fertility Centre). Oocyte donation outcome at Alpha International Fertility Centre. An International Journal of Obstetrics & Gynaecology 2012;119(S1):PP.137. Presented at the 10th Royal College of Obstetricians & Gynaecologists International Scientific Congress, 5-8 June 2012, Sarawak, Malaysia.

Donor egg program, Fresh Embryo Transfer, Non PGS
Mean no of embryos transferred : 2.4